产品货号：
Z25935
中文名称：
RYBP抗体
英文名称：
Anti-RYBP Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RYBP Antibody |
| 指标别名 | AAP1;APAP1;cb337;DEDAF;RYBP;rybpa;YEAF1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | RYBP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | DEDAF antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DEDAF.The immunogen is located within the last 50 amino acids of DEDAF. |
| 计算分子量 | 25kDa |
| 成分 | DEDAF Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | DEDAF Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | DEDAF antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD) death effector domain (DED),and caspase recruitment domain (CARD) containing molecules.Several molecules including caspases and adaptor FADD contain DEDs.A novel protein that interacts with DED of caspase-8 and 10,and FADD was identified recently and designated DEDAF for DED associated factor.DEDAF is identical to the transcriptional repressor RYBP.DEDAF/RYBP is expressed in multiple tissues and cell lines.DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane,and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis. |
| Uniprot ID | Q8N488 |
| 基因名全称 | RING1 and YY1 binding protein |
| 蛋白名全称 | RING1 and YY1 binding protein |
| 推荐稀释比 | DEDAF can be used for detection of DEDAF by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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